The Keystone Alliance of Sterile Processing Professionals (KASPP) chapter was originally formed in 2005 under the name "Keystone state Association of Sterile Processing Professionals." The name was changed when the chapter rechartered in 2025. 

The chapter's membership comprises members and associate members, totaling a membership of over two dozen in 2025. 

The chapter was awarded the Steris Small Chapter of the Year award in 2009, 2011, and 2015. The chapter continues to grow and offer current, relative, and applicable education sessions quarterly. It is in the seventeenth year of offering a six-credit all-day educational seminar.

KASPP members enjoy the ability to easily network with others in the profession and keep informed of innovations and trends in the healthcare field.